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Study of kaempferol in the treatment of rheumatoid arthritis through modulation of the NLRP3/CASP1/GSDMD axis and T-cell activation: Based on network pharmacology, single-cell analysis, and experimental validation

Xiaoyu He, Tianyu Wu, Haohua He, Lili Chen, Ke Han, Jiaqian Zheng, Zheng Zhang, Shuqi Yuan, Yanxin Wang, Yan Zhang, Xiaonan Zhang, Changhao Xie, Xiaonan Zhang, Changhao Xie

2024International Immunopharmacology31 citationsDOI

Topics & Concepts

Rheumatoid arthritisKaempferolPharmacologyMedicineCellChemistryComputational biologyBiologyBiochemistryInternal medicineQuercetinAntioxidantRheumatoid Arthritis Research and TherapiesSingle-cell and spatial transcriptomicsFerroptosis and cancer prognosis
Study of kaempferol in the treatment of rheumatoid arthritis through modulation of the NLRP3/CASP1/GSDMD axis and T-cell activation: Based on network pharmacology, single-cell analysis, and experimental validation | Litcius