One-pot chemoenzymatic synthesis of glycolic acid from formaldehyde
Tianzhen Li, Zijian Tan, Zijing Tang, Pi Liu, Haifeng Liu, Leilei Zhu, Yanhe Ma
Abstract
Enzymatic carboligation coupled with selective oxidation converts formaldehyde to glycolic acid, a monomer of biodegradable polymers.
Topics & Concepts
Glycolic acidFormaldehydeChemistryOrganic chemistryCombinatorial chemistryLactic acidBiologyGeneticsBacteriaCarbon dioxide utilization in catalysisbiodegradable polymer synthesis and propertiesAsymmetric Hydrogenation and Catalysis