Longin R-SNARE is retrieved from the plasma membrane by ANTH domain-containing proteins in <i>Arabidopsis</i>
Masaru Fujimoto, Kazuo Ebine, Kohji Nishimura, Nobuhiro Tsutsumi, Takashi Ueda
Abstract
Significance The plasma membrane (PM) acts as the interface between intra- and extracellular environments and is thus important for intercellular communication and extracellular signal perception. The composition and amounts of PM proteins are tightly regulated, by molecular mechanisms that remain largely unknown in plant cells. We identified a pair of ANTH domain-containing proteins functioning as adaptors for the retrieval of VAMP72 members, which are components of the membrane fusion machinery, during clathrin-mediated endocytosis. Our results further indicate that the recycling mechanisms of homologous VAMP7 proteins are different in plants and animals, suggesting a divergence of the endocytosis mechanism between these two kingdoms.