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Useful road maps: studying Drosophila larva’s central nervous system with the help of connectomics

Claire Eschbach, Marta Zlatic

2020Current Opinion in Neurobiology73 citationsDOIOpen Access PDF

Abstract

The larva of Drosophila melanogaster is emerging as a powerful model system for comprehensive brain-wide understanding of the circuit implementation of neural computations. With an unprecedented amount of tools in hand, including synaptic-resolution connectomics, whole-brain imaging, and genetic tools for selective targeting of single neuron types, it is possible to dissect which circuits and computations are at work behind behaviors that have an interesting level of complexity. Here we present some of the recent advances regarding multisensory integration, learning, and action selection in Drosophila larva.

Topics & Concepts

ConnectomicsNeuroscienceDrosophila melanogasterConnectomeDrosophila (subgenus)Computer scienceBiologyBiological neural networkFunctional connectivityBiochemistryGeneNeurobiology and Insect Physiology ResearchAnimal Behavior and ReproductionPhysiological and biochemical adaptations
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