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Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species

Linli Wang, Min Wang, Haiming Niu, Yaping Zhi, Shasha Li, Xuemin He, Zhitao Ren, Shiyi Wen, Lin Wu, Siying Wen, Rui Zhang, Zheyao Wen, Jing Yang, Ximei Zhang, Yanming Chen, Xiaoxian Qian, Guojun Shi

2024Journal of Molecular and Cellular Cardiology20 citationsDOI

Topics & Concepts

Unfolded protein responseSenescenceEndoplasmic reticulumEndoplasmic-reticulum-associated protein degradationCell biologyReactive oxygen speciesUbiquitin ligaseBiologyVascular smooth muscleOxidative stressMitochondrionEndocrinologyInternal medicineBiochemistryUbiquitinMedicineGeneSmooth muscleEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyUbiquitin and proteasome pathways
Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species | Litcius