Radical cyclization of alkynyl aryl ketones for the synthesis of 3-seleno-substituted thiochromones and chromones
Ricardo H. Bartz, Krigor B. Silva, Thiago J. Peglow, Angelita M. Barcellos, Raquel G. Jacob, Eder J. Lenardão, Gelson Perin
Abstract
Herein we present an alternative and transition-metal-free procedure to access 3-organoselanylthiochromones and 3-organoselanylchromones from the cyclization reaction between alkynyl aryl ketones and diorganyl diselenides promoted by Oxone®.
Topics & Concepts
ChemistryOxidizing agentArylCombinatorial chemistryReaction conditionsSurface modificationFunctional groupOrganic chemistryMedicinal chemistryCatalysisAlkylPolymerPhysical chemistrySynthesis of Organic CompoundsSulfur-Based Synthesis TechniquesOrganoselenium and organotellurium chemistry