SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis
Yafeng Gao, Wenhui Li, Zhenghao Wang, Cangang Zhang, Yaping He, Xiaowei Liu, Kexin Tang, Weiguo Zhang, Qiaoming Long, Yong Liu, Jinping Zhang, Baojun Zhang, Lianjun Zhang
Topics & Concepts
Endoplasmic-reticulum-associated protein degradationCell biologyUnfolded protein responsemTORC1Endoplasmic reticulumBiologyHomeostasisCD8ProteasomeT cellSignal transductionReceptorImmunologyImmune systemProtein kinase BBiochemistryPancreatic function and diabetesPhagocytosis and Immune RegulationEndoplasmic Reticulum Stress and Disease