Molecular AND logic gate for multiple single-nucleotide mutations detection based on CRISPR/Cas9n system-trigged signal amplification
Weidan Chang, Weipeng Liu, Haoran Shen, Sisi Chen, Peizhen Liao, Yingju Liu
Topics & Concepts
CRISPRNucleic acidLoop-mediated isothermal amplificationCas9ChemistryDNAComputational biologyLocus (genetics)GeneticsBiologyGeneBiochemistryCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanisms