Hippocampal Galectin-3 knockdown alleviates lipopolysaccharide-induced neurotoxicity and cognitive deficits by inhibiting TLR4/NF-кB signaling in aged mice
Fang Chen, Xiaofeng Wu, Jiayong Yang, Xuben Yu, Bili Liu, Zhiwen Yan
Topics & Concepts
NeuroinflammationGene knockdownNeurotoxicityHippocampal formationTLR4LipopolysaccharideNF-κBSignal transductionChemistryPharmacologyImmunologyCancer researchBiologyCell biologyMedicineApoptosisEndocrinologyInternal medicineInflammationBiochemistryToxicityGalectins and Cancer BiologyMacrophage Migration Inhibitory FactorNeuroinflammation and Neurodegeneration Mechanisms