Targeting ROS production through inhibition of NADPH oxidases
Joana Reis, Christoph Gorgulla, Marta Massari, Sara Marchese, Sérgio Valente, Beatrice Noce, Lorenzo Basile, Ricarda Törner, Huel Cox, Thibault Viennet, Moon Hee Yang, Melissa M. Ronan, Matthew G. Rees, Jennifer A. Roth, Lucia Capasso, Angela Nebbioso, Lucia Altucci, Antonello Mai, Haribabu Arthanari, Andrea Mattevi
Topics & Concepts
Reactive oxygen speciesCancer cellEnzymeBiochemistryDrug discoveryNADPH oxidaseHigh-throughput screeningCell biologyIn silicoChemistryTransmembrane proteinBiologyCancerReceptorGeneGeneticsNeutrophil, Myeloperoxidase and Oxidative MechanismsNanoplatforms for cancer theranosticsImmune cells in cancer