A benzothiazole-based dual reaction site fluorescent probe for the selective detection of hydrazine in water and live cells
Anwesha Maiti, Saikat Kumar Manna, Satyajit Halder, Moumi Mandal, Anirban Karak, Dipanjan Banik, Kuladip Jana, Ajit Kumar Mahapatra
Abstract
hydrazine-induced lactone ring-opening followed by selective cleavage of the dicyanovinyl group. According to the literature, dicyanovinyl group assisted lactone ring opening has revealed the possibility of hydrazine recognition with a large Stokes shift (140 nm) and a high fluorescence quantum yield (0.67). Here, the DFT study and practical applications of the probe BTC in different water samples have been presented. The probe BTC was also successfully applied for the detection of hydrazine in the vapor phase using paper strips and in live MDA-MB 231 cells.
Topics & Concepts
BenzothiazoleHydrazine (antidepressant)FluorescenceDual (grammatical number)ChemistryPhotochemistryCombinatorial chemistryOrganic chemistryChromatographyLiteratureArtPhysicsQuantum mechanicsMolecular Sensors and Ion DetectionElectrochemical sensors and biosensorsLuminescence and Fluorescent Materials