A tau dephosphorylation-targeting chimera selectively recruits protein phosphatase-1 to ameliorate Alzheimer’s disease and tauopathies
Yue Xiao, Linyu Wei, Jingfen Su, Huiyang Lei, Fei Sun, Mengzhu Li, Shihong Li, Xiaochuan Wang, Jie Zheng, Jian–Zhi Wang
Topics & Concepts
DephosphorylationDiseaseTau proteinTau pathologyProtein phosphatase 2PhosphataseAlzheimer's diseaseMedicineGerontologyNeuroscienceBiologyPhosphorylationInternal medicineBiochemistryAlzheimer's disease research and treatments14-3-3 protein interactionsCholinesterase and Neurodegenerative Diseases