Electrochemical Behavior of a Copper Tungstate-Fabricated Disposable Strip for the Rapid and Real-Time Detection of Uric Acid
Balasubramanian Sriram, S. Shanavas, Yung‐Fu Hsu, Sea‐Fue Wang, Mohammad Abu Haija
Abstract
Researchers are now aiming to develop multifunctional materials that are nontoxic, minimal in cost, and simple to produce and have superior efficiency for large-scale electrochemical sensor applications. Uric acid (UA) is a biomarker correlated with gout and kidney stones that has an adverse effect on the human body. Here, UA was measured using differential pulse voltammetry (DPV) and amperometric (i–t) techniques with a superactive Wolframite structure of CuWO4. CuWO4 was characterized using a variety of microscopic and spectroscopic methods. The data collected indicated that the electrode modified with CuWO4 provides a superior electrochemical oxidation peak current compared with the bare electrode. CuWO4 exhibits wide linear ranges, with a lower limit of detection obtained from DPV and i–t techniques. Furthermore, the CuWO4-modified sensor has been used to determine the concentration of UA in urine and bovine serum albumin samples. Moreover, the CuWO4-modified sensor has great stability and reproducibility.