Hydroxamic acid hybrids: Histone deacetylase inhibitors with anticancer therapeutic potency
Yuan Jiang Pan, Haodong Hou, Bo Zhou, Jingyue Gao, Feng Gao, Feng Gao
Topics & Concepts
Histone deacetylaseHydroxamic acidChemistryVorinostatHistonePharmacophoreCell cycle checkpointRational designHistone deacetylase inhibitorSmall moleculeAcetylationCancer researchPharmacologyBiochemistryCell cycleApoptosisBiologyGeneGeneticsStereochemistryHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsPeptidase Inhibition and Analysis