Determination of individual oligonucleotide impurities by small amine ion pair-RP HPLC MS and MS/MS: n − 1 impurities
Stilianos G. Roussis, Andrew Rodriguez, Claus Rentel
Topics & Concepts
ChemistryReagentImpurityChromatographyAlkylResolution (logic)Amine gas treatingMass spectrometryHigh-performance liquid chromatographyOligonucleotideAnalytical Chemistry (journal)Organic chemistryBiochemistryArtificial intelligenceComputer scienceDNADNA and Nucleic Acid ChemistryAnalytical Chemistry and ChromatographyMicrofluidic and Capillary Electrophoresis Applications