Co-delivery of gemcitabine prodrug along with anti NF-κB siRNA by tri-layer micelles can increase cytotoxicity, uptake and accumulation of the system in the cancers
Parisa Norouzi, Mohsen Amini, Rassoul Dinarvand, Ehsan Arefian, Ehsan Seyedjafari, Fatemeh Atyabi
Topics & Concepts
GemcitabineProdrugNanocarriersCytotoxicityMicelleIn vivoMaterials sciencePolyethylene glycolApoptosisDrug deliveryPharmacologyCancer researchCancer cellChemotherapyCancerIn vitroChemistryMedicineNanotechnologyBiochemistryBiologyOrganic chemistryAqueous solutionInternal medicineSurgeryBiotechnologyNanoparticle-Based Drug DeliveryRNA Interference and Gene DeliveryNanoplatforms for cancer theranostics