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Flexible, stretchable, and single-molecule-sensitive SERS-active sensor for wearable biosensing applications

Muhammad Aminul Haque Chowdhury, Nishat Tasnim, Mainul Hossain, Ahsan Habib

2023RSC Advances25 citationsDOIOpen Access PDF

Abstract

, along with other long-desired characteristics for SERS applications such as a high scattering to absorption ratio (∼2.5) and a large hotspot volume (40 nm × 40 nm × 5 nm). To achieve flexibility, we use polydimethylsiloxane (PDMS) as the substrate, which is stable, transparent, and biologically compatible. Our numerical calculations show that the proposed sensor offers reliable SERS performance even under bending (up to 100° angles) or stretching (up to 50% stretch). The easy-to-fabricate and flexible nature of our sensor offers a promising avenue for developing highly sensitive wearable sensors for a range of applications, particularly in the field of personalized medicine and remote patient monitoring.

Topics & Concepts

Wearable computerMaterials scienceNanotechnologyBiosensorRaman scatteringFlexibility (engineering)Wearable technologyPolydimethylsiloxaneComputer scienceRaman spectroscopyEmbedded systemOpticsStatisticsPhysicsMathematicsAdvanced Sensor and Energy Harvesting MaterialsNanoplatforms for cancer theranosticsBiosensors and Analytical Detection
Flexible, stretchable, and single-molecule-sensitive SERS-active sensor for wearable biosensing applications | Litcius