Catalytic asymmetric conjugate addition of indolizines to unsaturated ketones catalyzed by chiral-at-metal complexes
Cheng Huang, Zhifei Zhao, Shiwu Li, Jixing Zhao, Leifang Wu, Cheng‐Zhi Gu
Abstract
A highly enantioselective conjugate addition of indolizine and its analogues with α,β-unsaturated 2-acyl imidazoles has been developed.
Topics & Concepts
ChemistryConjugateCatalysisEnantioselective synthesisMetalOrganic chemistryCombinatorial chemistryMathematical analysisMathematicsSynthesis and Reactivity of HeterocyclesCyclopropane Reaction MechanismsSynthesis and Characterization of Pyrroles