Estimation and mapping of the missing heritability of human phenotypes
Pierrick Wainschtein, Yuanxiang Zhang, Jeremy Schwartzentruber, Irfahan Kassam, Julia Sidorenko, Petko Fiziev, Huanwei Wang, Jeremy F. McRae, Richard Border, Noah Zaitlen, Sriram Sankararaman, Michael E. Goddard, Jian Zeng, Peter M. Visscher, Kyle Kai‐How Farh, Loïc Yengo
Topics & Concepts
HeritabilityBiologyGeneticsMissing heritability problemIndelGenetic associationAllelePhenotypeMinor allele frequencyEvolutionary biologyQuantitative trait locusAllele frequencyGenetic variantsGenetic variationGenome-wide association studyCoding regionINDEL MutationGeneSequence (biology)PolygeneAssociation testEstimationHuman genetic variationGenotypeAdditive genetic effectsGenetic Associations and EpidemiologyGenomics and Rare DiseasesBioinformatics and Genomic Networks