A stereochemical journey around spirocyclic glutamic acid analogs
Anton V. Chernykh, Alla V. Chernykh, Dmytro S. Radchenko, Pratik Rajesh Chheda, Едуард Б. Русанов, Oleksandr O. Grygorenko, M. Ashley Spies, Dmitriy M. Volochnyuk, Igor V. Komarov
Abstract
A practical divergent synthetic approach is reported for the library of regio- and stereoisomers of glutamic acid analogs built on the spiro[3.3]heptane scaffold.
Topics & Concepts
ChemistryStereochemistryHydroxymethylAbsolute configurationRing (chemistry)Derivative (finance)StereoisomerismCombinatorial chemistryMoleculeOrganic chemistryFinancial economicsEconomicsChemical Synthesis and AnalysisAsymmetric Synthesis and CatalysisSynthetic Organic Chemistry Methods