Modulation of PKM activity affects the differentiation of T <sub>H</sub> 17 cells
Scott M. Seki, Kacper Posyniak, Rebecca L. McCloud, Dorian A. Rosen, Anthony Fernández-Castañeda, Rebecca M. Beiter, Vlad Serbulea, Sarah C. Nanziri, Nikolas W. Hayes, Charles Spivey, Lelisa Gemta, Timothy N. J. Bullock, Ku‐Lung Hsu, Alban Gaultier
Abstract
17 and regulatory T cells. Collectively, our data clarify the therapeutic potential of PKM2 activators in MS-like disease and how these agents alter T cell function.
Topics & Concepts
Cell biologyModulation (music)ChemistryBiologyPhysicsAcousticsAdenosine and Purinergic SignalingImmune Cell Function and InteractionAcute Lymphoblastic Leukemia research