Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration
Yi‐Ting Tsai, Yao Li, Joseph Ryu, Pei-Yin Su, Chia-Hua Cheng, Wen-Hsuan Wu, Yong-Shi Li, Peter M. J. Quinn, Kam W. Leong, Stephen H. Tsang
Topics & Concepts
Retinal pigment epitheliumMacular degenerationDownregulation and upregulationCell biologyDrusenBiologyLipid metabolismCholesterolInduced pluripotent stem cellEffluxABCA1OxysterolRetinalEndocrinologyBiochemistryMedicineGeneTransporterOphthalmologyEmbryonic stem cellRetinal Diseases and TreatmentsRetinal Development and DisordersRetinopathy of Prematurity Studies