Characterization of temporospatial distribution of renal tubular casts by nephron tracking after ischemia-reperfusion injury
Naomi S. Shin, Arnaud Marlier, Leyuan Xu, TuKiet T. Lam, Lloyd G. Cantley, Jian-Kan Guo
Abstract
This detailed characterization of the dynamic distribution of dead cell debris in ischemically injured kidney tubules reveals which cells in the kidney are most severely injured, when and where tubular casts form, and when (and to a lesser extent, how) they are cleared.
Topics & Concepts
NephronClearanceKidneyIschemiaMedicineRenal functionDistribution (mathematics)Internal medicineCardiologyPathologyUrologyMathematicsMathematical analysisAcute Kidney Injury ResearchOrgan Donation and TransplantationOrgan Transplantation Techniques and Outcomes