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NAG-1/GDF15 protects against streptozotocin-induced type 1 diabetes by inhibiting apoptosis, preserving beta-cell function, and suppressing inflammation in pancreatic islets

Ying Wang, Jiajun Chen, Tingting Sang, Chaojie Chen, Peng He, Xiaojian Lin, Qian Zhao, Shengjia Chen, Thomas E. Eling, Xingya Wang

2022Molecular and Cellular Endocrinology22 citationsDOI

Topics & Concepts

IsletInternal medicineEndocrinologyGDF15StreptozotocinInflammationPancreatic isletsApoptosisDiabetes mellitusBeta cellInsulinInsulin resistanceType 2 diabetesMedicineBiologyBiochemistryGDF15 and Related BiomarkersNutrition and Health in AgingNuclear Receptors and Signaling
NAG-1/GDF15 protects against streptozotocin-induced type 1 diabetes by inhibiting apoptosis, preserving beta-cell function, and suppressing inflammation in pancreatic islets | Litcius