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Inhibition of NSUN6 protects against intermittent hypoxia-induced oxidative stress and inflammatory response in adipose tissue through suppressing macrophage ferroptosis and M1 polarization

Xinyu Wang, Xinyu Wang, Linjing Gong, Chang Wei, Yuean Zhao, Longyi Ran, Peijun Li, Wenyu Gu, Xu Wu, Zongan Liang, Xinyuan Wang, Xinyuan Wang

2025Life Sciences16 citationsDOI

Topics & Concepts

Oxidative stressMacrophage polarizationAdipose tissueHypoxia (environmental)InflammationAdipose tissue macrophagesCell biologyChemistryMacrophageOxidative phosphorylationEndocrinologyMedicineInternal medicineBiologyWhite adipose tissueOxygenBiochemistryIn vitroOrganic chemistryFerroptosis and cancer prognosisImmune cells in cancerCancer, Hypoxia, and Metabolism
Inhibition of NSUN6 protects against intermittent hypoxia-induced oxidative stress and inflammatory response in adipose tissue through suppressing macrophage ferroptosis and M1 polarization | Litcius