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Dichotomous engagement of HDAC3 activity governs inflammatory responses

Hoang C.B. Nguyen, Marine Adlanmérini, Amy K. Hauck, Mitchell A. Lazar

2020Nature150 citationsDOIOpen Access PDF

Topics & Concepts

HDAC3Histone deacetylaseNuclear receptorTranscription factorHistoneCell biologyPsychological repressionChemistryRepressorActivator (genetics)ChromatinReceptorBiologyBiochemistryGeneGene expressionHistone Deacetylase Inhibitors ResearchNF-κB Signaling PathwaysGenomics, phytochemicals, and oxidative stress
Dichotomous engagement of HDAC3 activity governs inflammatory responses | Litcius