Different changes in the biomarker C-terminal telopeptides of type II collagen (CTX-II) following intra-articular injection of high molecular weight hyaluronic acid and oral non-steroidal anti-inflammatory drugs in patients with knee osteoarthritis: a multi-center randomized controlled study
Muneaki Ishijima, Tomohiro Nakamura, Katsuji Shimizu, Kunihiko Hayashi, H. Kikuchi, Satoshi Soen, Go Omori, Toshihiko Yamashita, Yuji Uchio, Junji Chiba, Yuki Ideno, Mitsuaki Kubota, Haruka Kaneko, H. Kurosawa, Kazunari Kaneko
Topics & Concepts
Hyaluronic acidType I collagenIntra articularBiomarkerChemistryCollagen, type I, alpha 1Type II collagenMedicineInternal medicineBiochemistryPathologyArthritisOsteoarthritisAnatomyExtracellular matrixAlternative medicineOsteoarthritis Treatment and MechanismsProteoglycans and glycosaminoglycans researchCollagen: Extraction and Characterization