Simultaneous single-cell genome and transcriptome sequencing in nanoliter droplet with digital microfluidics identifying essential driving genes
Xing Xu, Li Lin, Jian Yang, Weizhou Qian, Rui Su, Xiaoxu Guo, Linfeng Cai, Zirun Zhao, Jia Song, Chaoyong Yang
Topics & Concepts
TranscriptomeBiologyComputational biologySingle cell sequencingGenomeDigital polymerase chain reactionDNA sequencingGeneSingle-cell analysisRNA-SeqGeneticsCellPhenotypeExome sequencingGene expressionPolymerase chain reactionSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsAdvanced biosensing and bioanalysis techniques