Low SP1 SUMOylation-dependent SNHG17 upregulation promotes drug resistance of gastric cancer through impairing hsa-miR-23b-3p-induced Notch2 inhibition
Guoyu Huang, Guohao Cai, Dongwei Hu, Jinjie Li, Qigang Xu, Zongjing Chen, Bo Xu
Topics & Concepts
SUMO proteinDownregulation and upregulationmicroRNAGene silencingCancer researchSp1 transcription factorCisplatinBiologyIn vivoChemistryMolecular biologyPromoterGene expressionBiochemistryChemotherapyGeneGeneticsUbiquitinRNA Research and SplicingMicroRNA in disease regulationCancer-related molecular mechanisms research