Laboratory perspectives in the development of polygenic risk scores for disease: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)
Honey V. Reddi, Hannah Wand, Birgit Funke, Michael T. Zimmermann, Matthew S. Lebo, Emily Qian, Brian H. Shirts, Ying Zou, Bing Zhang, Nancy C. Rose, Aya Abu‐El‐Haija
Topics & Concepts
DiseasePolygenic risk scoreMedical geneticsGenomicsMultifactorial InheritanceAutismMedicineBioinformaticsGeneticsBiologyPsychiatryGenomePathologySingle-nucleotide polymorphismGenotypeGeneGenetic Associations and EpidemiologyGenomics and Rare DiseasesBRCA gene mutations in cancer