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Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

Paula García-Huerta, Paulina Troncoso-Escudero, Di Wu, Arun Thiruvalluvan, Marisol Cisternas-Olmedo, Daniel R. Henríquez, Lars Plate, Pedro Chaná‐Cuevas, Cristian Saquel, Peter Thielen, Kenneth Longo, Brad J. Geddes, Gerardo Z. Lederkremer, Neeraj Sharma, Marina Shenkman, Swati Naphade, S. Pablo Sardi, Carlos Spichiger, Hans Richter, Felipe A. Court, Kizito‐Tshitoko Tshilenge, Lisa Ellerby, R. Luke Wiseman, Christian González‐Billault, Steven Bergink, René L. Vidal, Claudio Hetz

2020Acta Neuropathologica71 citationsDOIOpen Access PDF

Topics & Concepts

Huntington's diseaseExtracellularInsulin-like growth factorGrowth factorInsulinDiseaseInsulin-like growth factor 2Cell biologyInternal medicineChemistryEndocrinologyBiologyMedicineReceptorGenetic Neurodegenerative DiseasesEndoplasmic Reticulum Stress and DiseaseMuscle Physiology and Disorders
Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates | Litcius