Carrageenan-Based Compounds as Wound Healing Materials
Bogdan Neamţu, Andreea Barbu, Mihai Octavian Negrea, Cristian Stefan Berghea-Neamtu, Dragoș Popescu, Marius Zăhan, Vioara Mireşan
Abstract
The following review is focused on carrageenan, a heteroglycan-based substance that is a very significant wound healing biomaterial. Every biomaterial has advantages and weaknesses of its own, but these drawbacks are typically outweighed by combining the material in various ways with other substances. Carrageenans' key benefits include their water solubility, which enables them to keep the wound and periwound damp and absorb the wound exudate. They have low cytotoxicity, antimicrobial and antioxidant qualities, do not stick to the wound bed, and hence do not cause pain when removed from the wounded region. When combined with other materials, they can aid in hemostasis. This review emphasizes the advantages of using carrageenan for wound healing, including the use of several mixes that improve its properties.