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Tadalafil and bergapten mitigate streptozotocin-induced sporadic Alzheimer's disease in mice via modulating neuroinflammation, PI3K/Akt, Wnt/β-catenin, AMPK/mTOR signaling pathways

Mohamed A. Salem, Barbara Budzyńska, Joanna Kowalczyk, Nesrine S. El Sayed, Suzan M. Mansour

2021Toxicology and Applied Pharmacology58 citationsDOI

Topics & Concepts

NeuroinflammationMorris water navigation taskNeuroprotectionPI3K/AKT/mTOR pathwayProtein kinase BWnt signaling pathwayPharmacologyChemistryEndocrinologyMedicineInternal medicineSignal transductionHippocampal formationBiologyCell biologyInflammationAlzheimer's disease research and treatmentsTryptophan and brain disordersCholinesterase and Neurodegenerative Diseases
Tadalafil and bergapten mitigate streptozotocin-induced sporadic Alzheimer's disease in mice via modulating neuroinflammation, PI3K/Akt, Wnt/β-catenin, AMPK/mTOR signaling pathways | Litcius