Molecular and in vivo phenotyping of missense variants of the human glucagon receptor
Wijnand J. C. van der Velden, Peter Lindquist, Jakob Sture Madsen, Roderick H.M.J. Stassen, Nicolai J. Wewer Albrechtsen, Jens J. Holst, Alexander S. Hauser, Mette M. Rosenkilde
Abstract
is the main signaling pathway effecting the physiological roles of the glucagon receptor.
Topics & Concepts
Missense mutationIn vivoReceptorBiologyGlucagon receptorGlucagonGeneticsComputational biologyMutationBiochemistryGeneHormoneDiabetes Treatment and ManagementReceptor Mechanisms and SignalingPancreatic function and diabetes