Gambogenic acid induces Noxa-mediated apoptosis in colorectal cancer through ROS-dependent activation of IRE1α/JNK
Qun Zhao, Jing Zhong, Yun Bi, Yongqiang Liu, Yingxiang Liu, Jian Guo, Longrui Pan, Yan Tan, Xianjun Yu
Topics & Concepts
In vivoApoptosisChemistryPhosphorylationKinaseViability assayUnfolded protein responseCancer researchBiologyCell biologyBiochemistryBiotechnologyNatural Compound Pharmacology StudiesBioactive Compounds and Antitumor AgentsPhytochemistry and Biological Activities