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Cutaneous lupus erythematosus/lichen planus overlap syndrome

Katherine Jicha, David Wang, Jayson Miedema, Luis Alfonso Díaz‐Martínez

2021JAAD Case Reports14 citationsDOIOpen Access PDF

Abstract

Cutaneous lupus erythematosus (CLE) and lichen planus (LP) are considered skin disease processes with distinct pathogenic mechanisms, clinical features, histologic findings, and disease courses. However, there exists a rare disorder termed CLE/LP overlap syndrome that has been inconsistently reported in the literature due to the absence of clear diagnostic criteria, with most reports involving cases with coexisting or overlapping clinical and histologic features of CLE and LP.1-3 In this article, we report 2 cases of CLE/LP overlap syndrome, propose a diagnostic criterion for CLE/LP overlap syndrome, and briefly review the literature and classify previously reported cases under our proposed criterion.

Topics & Concepts

MedicineOverlap syndromeCutaneous Lupus ErythematosusDermatologyDiseaseSystemic lupus erythematosusLupus erythematosusPathologyImmunologyAntibodyAutoimmune Bullous Skin DiseasesOral Health Pathology and TreatmentSystemic Lupus Erythematosus Research
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