HepG2 (C3A) spheroids show higher sensitivity compared to HepaRG spheroids for drug-induced liver injury (DILI)
Aneesha Basharat, Helen Rollison, Dominic P. Williams, Delyan P. Ivanov
Topics & Concepts
SpheroidCmaxDrugLiver injuryPharmacologyCell cultureChemistryMedicineBiologyPharmacokineticsGeneticsDrug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug MetabolismLiver physiology and pathology