Intestinal toxicity alleviation and efficacy potentiation through therapeutic administration of <i>Lactobacillus paracasei</i> GY-1 in the treatment of gout flares with colchicine
Jiaqi Zeng, Yan Li, Yizhi Zou, Ying Yang, Tingting Yang, Yizhuang Zhou
Abstract
sp., which may contribute to its therapeutic efficacy. This study demonstrates the feasibility of developing probiotic-based adjuvant therapy or bacteriotherapy for treating gout flares. To our knowledge, GY-1 is the first probiotic that could be used as an alternative synergetic agent with COL for the therapeutic treatment of gout flares.
Topics & Concepts
ColchicineGoutPharmacologyToxicityLactobacillus paracaseiMedicineTherapeutic effectProbioticInternal medicineBiologyBacteriaGeneticsGout, Hyperuricemia, Uric AcidClostridium difficile and Clostridium perfringens researchVeterinary medicine and infectious diseases