Personalized neoantigen vaccination with synthetic long peptides: recent advances and future perspectives
Xiaotong Chen, Ju Yang, Lifeng Wang, Baorui Liu
Abstract
T cell responses. This review will introduce the history of long peptide-based neoantigen vaccines, discuss their advantages, summarize current preclinical and clinical developments, and propose future perspectives.
Topics & Concepts
ImmunotherapyCancer immunotherapyAntigenImmunologyCD8Computational biologyImmune systemVaccinationMedicineBiologyImmunotherapy and Immune Responsesvaccines and immunoinformatics approachesRNA Interference and Gene Delivery