CD4+ T cells engineered with FVIII-CAR and murine Foxp3 suppress anti-factor VIII immune responses in hemophilia a mice
Richard Y. Fu, Alex C. Chen, Meghan J. Lyle, Chun‐Yu Chen, Chao-Lien Liu, Carol H. Miao
Topics & Concepts
FOXP3ImmunologyImmune systemAntigenIL-2 receptorBiologyAdoptive cell transferFactor IXChimeric antigen receptorImmune toleranceCancer researchT cellGeneticsCAR-T cell therapy researchViral Infectious Diseases and Gene Expression in InsectsVirus-based gene therapy research