Targeting Lysine-Specific Demethylase 1 Rescues Major Histocompatibility Complex Class I Antigen Presentation and Overcomes Programmed Death-Ligand 1 Blockade Resistance in SCLC
Evelyn M. Nguyen, Hirokazu Taniguchi, Joseph M. Chan, Yingqian A. Zhan, Xiaoping Chen, Juan Qiu, Elisa de Stanchina, Viola Allaj, Nisargbhai Shah, Fathema Uddin, Parvathy Manoj, Michael Liu, Sheng F. Cai, Ross L. Levine, Àlvaro Quintanal-Villalonga, Triparna Sen, Andrew Chow, Charles M. Rudin
Topics & Concepts
Major histocompatibility complexImmune checkpointAntigen presentationCancer researchImmune systemMHC class IT cellBiologyImmunotherapyImmunologyMedicineLung Cancer Research StudiesImmune Response and InflammationImmunotherapy and Immune Responses