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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

Megan L. Clark, Kamen P. Simeonov, Walter K. Mowel, Michaël F. Michieletto, Leonel Joannas, Jasmine M. Wright, Isabel Erickson, Lexus R. Johnson, Rakesh Krishnan, César de la Fuente‐Núñez, Andy J. Minn, Jorge Henao‐Mejia

2025Immunity15 citationsDOI

Topics & Concepts

BiologyImmunityInterferonCell biologyMitochondrionSignal transductionCancer researchImmunologyImmune systeminterferon and immune responsesImmune cells in cancerCytokine Signaling Pathways and Interactions
Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity | Litcius