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Specific RNA interactions promote TDP-43 multivalent phase separation and maintain liquid properties

Zachary R. Grese, Alliny C.S. Bastos, Lohany D. Mamede, Rachel L. French, Timothy M. Miller, Yuna M. Ayala

2021EMBO Reports130 citationsDOIOpen Access PDF

Topics & Concepts

RNARNA-binding proteinCell biologyBiologyStress granuleRibonucleoproteinChemistryNeurodegenerationMessenger RNABiochemistryGeneDiseaseMedicineTranslation (biology)Internal medicineRNA Research and SplicingAmyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research
Specific RNA interactions promote TDP-43 multivalent phase separation and maintain liquid properties | Litcius