HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
Yufeng Xiao, Seth Hale, Nikee Awasthee, Chengcheng Meng, Xuan Zhang, Yi Liu, Haocheng Ding, Zhiguang Huo, Dongwen Lv, Weizhou Zhang, Mei He, Guangrong Zheng, Daiqing Liao
Topics & Concepts
HDAC3AcetylationHDAC8Histone deacetylaseHistoneHistone deacetylase 5EpigeneticsHDAC11BiologyChemistryCell biologyBiochemistryGeneHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsUbiquitin and proteasome pathways