Bronchoscopic Cryobiopsy and Forceps Biopsy for the Diagnostic Evaluation of Diffuse Parenchymal Lung Disease in Clinical Practice
Matthew Koslow, Eric S. Edell, David E. Midthun, John J. Mullon, Ryan Kern, Darlene R. Nelson, Kenneth K. Sakata, Teng Moua, Anja C. Roden, Eunhee S. Yi, Janani Reisenauer, Paul A. Decker, Jay H. Ryu
Abstract
OBJECTIVE: To assess the contribution and safety of bronchoscopic cryobiopsy vs traditional forceps biopsy used in clinical practice for diagnosing diffuse parenchymal lung disease (DPLD). PATIENTS AND METHODS: was defined as a biopsy result deemed useful in patient management. RESULTS: =.20). CONCLUSION: Bronchoscopic cryobiopsy revealed higher diagnostic yield and clinical utility than did forceps biopsy. However, procedure-related complications were higher in the cryobiopsy group. The choice of bronchoscopic biopsy procedure for patients with DPLD depends on the clinicalradiologic context.