Combinatorial Approaches to Enhance DNA Damage following Enzyme-Mediated Depletion of L-Cys for Treatment of Pancreatic Cancer
Achinto Saha, Shengyuan Zhao, Zhao Chen, George Georgiou, Everett Stone, Dawit Kidane, John DiGiovanni
Topics & Concepts
DNA damageCancer researchDNA repairBiologyOlaparibPancreatic cancerThioredoxin reductaseCancer cellPoly ADP ribose polymeraseCancerPARP inhibitorMolecular biologyThioredoxinDNAPolymeraseBiochemistryEnzymeGeneticsPancreatic and Hepatic Oncology ResearchEpigenetics and DNA MethylationCancer-related Molecular Pathways