Litcius/Paper detail

What makes Yarrowia lipolytica well suited for industry?

Young Kyoung Park, Rodrigo Ledesma‐Amaro

2022Trends in biotechnology191 citationsDOIOpen Access PDF

Abstract

Yarrowia lipolytica possesses natural and engineered traits that make it a good host for the industrial bioproduction of chemicals, fuels, foods, and pharmaceuticals. In recent years, academic and industrial researchers have assessed its potential, developed synthetic biology techniques, improved its features, scaled its processes, and identified its limitations. Both publications and patents related to Y. lipolytica have shown a drastic increase during the past decade. Here, we discuss the characteristics of this yeast that make it suitable for industry and the remaining challenges for its wider use at large scale. We present evidence herein that shows the importance and potential of Y. lipolytica in bioproduction such that it may soon be one of the preferred choices of industry.

Topics & Concepts

YarrowiaBiotechnologyBiochemical engineeringComputational biologyBiologyYeastEngineeringGeneticsMicrobial Metabolic Engineering and BioproductionBiofuel production and bioconversionEnzyme Catalysis and Immobilization