ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
Janice M. Leung, Chen Xi Yang, Anthony Raymond Tam, Tawimas Shaipanich, Tillie‐Louise Hackett, Gurpreet K. Singhera, Delbert R. Dorscheid, Don D. Sin
Abstract
<b>Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation.</b>https://bit.ly/3bC29es
Topics & Concepts
MedicineCOPDCoronavirus disease 2019 (COVID-19)AirwaySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakReceptorSmoking cessationVirusInternal medicineVirologyImmunologyPathologyAnesthesiaDiseaseOutbreakInfectious disease (medical specialty)Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchCancer, Stress, Anesthesia, and Immune Response