Single-cell and spatial profiling identify three response trajectories to pembrolizumab and radiation therapy in triple negative breast cancer
Stephen L. Shiao, Kenneth Gouin, Nathan Ing, Alice Y. Ho, Reva Basho, Aagam Shah, Richard H. Mebane, David Zitser, Andrew Martinez, Natalie-Ya Mevises, Bassem Ben-Cheikh, Regina M. Henson, Monica Mita, Philomena McAndrew, Scott Karlan, Armando E. Giuliano, Alice Chung, Farin Amersi, Catherine Dang, Heather Richardson, Wonwoo Shon, Farnaz Dadmanesh, M. Burnison, Amin Mirhadi, Zachary S. Zumsteg, Rachel Choi, Madison Davis, Joseph Lee, Dustin Rollins, Cynthia Martin, Negin Habibi Khameneh, Heather L. McArthur, Simon Knott
Topics & Concepts
Triple-negative breast cancerPembrolizumabBreast cancerProfiling (computer programming)Cancer researchRadiation therapyBiologyOncologyComputational biologyMedicineCancerInternal medicineComputer scienceImmunotherapyOperating systemSingle-cell and spatial transcriptomicsCancer Cells and MetastasisImmunotherapy and Immune Responses