Mechanism of conductance control and neurosteroid binding in NMDA receptors
Hyunook Kang, Ruben Steigerwald, Elijah Z. Ullman, Max Epstein, Srinu Paladugu, Dennis C. Liotta, Stephen F. Traynelis, Hiro Furukawa
Topics & Concepts
BiophysicsAllosteric regulationNeuroactive steroidConductanceNMDA receptorChemistryHelix (gastropod)Transmembrane domainCryo-electron microscopyProtein subunitIon channelReceptorTransmembrane proteinNeuroscienceCell biologyMechanism (biology)Protein structureBiologyPatch clampStructural biologyRandom hexamerLigand (biochemistry)BiochemistryPotassium channelBent molecular geometryNeuroscience and Neuropharmacology ResearchIon channel regulation and functionNeural dynamics and brain function